Moncayo Roy, Moncayo Helga.
We describe a small series of patients who were examined at a time post-COVID-19 infection. The main common complaint at presentation was fatigue. Using a previously described and clinically validated examination method based on 3D-Power Doppler sonography of the thyroid, we could identify signs of coenzyme Q10 (CoQ10) deficiency in these cases. In our previous investigations we have been able to correlate CoQ10 deficiency with a metabolic switch to glycolysis, i.e. a biochemical process with low ATP production output. Combined supplementation with magnesium, selenomethionine and CoQ10 improved the clinical condition. Signs of CoQ10 deficiency persisted in 2 cases where stress situation through workload persisted. Stress is a condition associated with low levels of CoQ10. We propose that CoQ10 deficiency can be involved in the pathogenesis of COVID-19 infection affecting physical performance, and potentially also heart function resulting in fatigue. Experimental and clinical data from the literature on the use of CoQ10 suggest that this compound should be considered in treatment strategies for COVID-19 patientsView pdf