Authors: Cid Siena, Bannerman Anita, Garduno-Diaz Sara D.
As rates of metabolic syndrome (MS) rise globally, it is unclear how and if the risk factors associated with this condition impact flavor perception via the retronasal pathway, which is critical for experiencing the flavor of foods and drinks. This commentary discusses existing literature on the possible impacts of MS on retronasal olfaction by examining primary diagnostic criteria, including hypertension, hyperglycemia, hypertriglyceridemia, hypoalphalipoproteinemia, and excess visceral adipose tissue. Risk factors for MS including hypertension, obesity, and hyperglycemia appear to have a negative impact on the sensitivity of retronasal olfaction. Although most of the work cited in this communication affirms that MS does negatively affect the functionality of the olfactory system, it is important to note that research is divided on this determination. Although retronasal dysfunction is not considered a life threating condition, it drastically changes the landscape of sensory information perceived and impacts an individual’s quality of life. Further clinical research on the impact of MS on retronasal olfaction is warranted to provide insights into the intricacies of these pathways.
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