Authors: Hamsatou CISSE, Youba SANGARE, Abdramane TRAORE, Nagou TOLO, Amadou KASSOGUE, Djeneba DIAGNE, Cheick Oumar SANOGO, Boureima KODIO, Abdoulaye Mamadou TRAORE, Garan DABO, Ghislain PODA, Brehima GUINDO, Daouda Kassoum MINTA.
Background: The emergence and spread of antibiotic resistance is a major public health threat. Worldwide, one of the main causes remains the unreasonable use of antibiotics.
Objective: To map bacterial infections and the resistances profile of antibacterials at Kati University Hospital.
Methodology: Transversal analytical study with prospective collection over a period of 20 months in the department of general medicine and urology of the BSS University Hospital of Kati.
Results: 102 patients participated in this study with an average age of 55.5 years. Almost a quarter (72.5%) of participants were men. Less than half were patients aged 60 years. The biologics examined involved urine (78.4 %), pus (16%), blood (12.7%), stool (2%) samples. The main germs isolated were: Escherichia coli (52.9%); Klebsiella pneumonia (14.5%); Staphylococcus aureus (9.9%); Acinetobacter baumannii and Enteroccocus faecium (4.9%). The level of resistance of Escherichia coli and Klebsiella pneumoniae was high to ampicillin, amoxicillin-clavulanic acid; cotrimoxazole; moderately elevated to C3G, and fluoroquinolones with relative sensitivity to aminoglycosides. Imifpenem, Amikacin, Ertapenème were the most active antibiotics. Staphylococci were resistant to penicillin, with ciprofloxacin and oxacillin. Thus, Acinetobacter baumannii had a high level of resistance to C3G, Ticarcillin, Cotrimoxazole and Piperacillin-tazobactam. Enteroccocus faecium had strong resistance to Cotrimoxazole and Ciprofloxacin.
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