Stem Cell and Regenerative Medicine

Open Access ISSN: 2639-9512

Abstract


Effect and Potential Mechanism of Local Injection of Umbilical Cord Mesenchymal Stem Cells in the Treatment of Knee Injury

Authors: Shaoshan Wang, Xiaohui Cui, Rongrong Li, Xinyi Shi, Xiaoxia Jiang, Chongmei Li, Taihua Wang

Objective: To analyze the effect and potential mechanism of local injection of umbilical cord mesenchymal stem cells in the treatment of knee injury.

Methods: A total of 74 patients with knee joint injury were selected as research objects from March 2018 to December 2020. They were divided into the reference group (37 cases) and the study group (37 cases). The study group was treated with local injection of umbilical cord mesenchymal stem cells, while the reference group was treated with conventional treatment, and the therapeutic effect was compared.

Results: The FMA score of the experimental group was significantly better than that of the control group 1 month and 2 months after treatment, the difference was statistically significant (P<0.05). The results showed that the scores of the study group were better (28.62 ± 4.45) and (34.54 ± 4.34). In addition, the effective rate of treatment in the study group was significantly higher than that in the reference group (P<0.05). The score of pain degree after treatment in the study group was significantly lower than that in the reference group, and the difference was P<0.05.

Conclusion: Local injection of umbilical cord mesenchymal stem cells in the treatment of knee injury can effectively enhance the limb function of patients, relieve clinical symptoms, eliminate pain, and increase the effective rate of treatment.

View/Download pdf