Authors: Carlos Alberto Paterno Marchioli.
Hypertensive Cardiovascular Disease is a complex, multifactorial, and chronic illness, frequently beginning during childhood or adolescence, could develop functional and/or structural cardiovascular organ damage by the increase of the volume/pressure level and the arterial stiffness, even before it exceeds the “normal” systolic and diastolic blood pressure levels. In the last decades, the pulsatile arterial function has been increasingly recognized as a major determinant of cardiovascular risk. It is known that hypertension is the most prevalent independent risk factor for atrial fibrillation in the population. Both structural remodelling and subsequent electrophysiological changes by atrial fibrosis constitute an arrhythmogenic substrate for the induction and maintenance of atrial fibrillation.
Atrial fibrillation has been associated with stroke, heart failure, and cardiovascular mortality. The research of non-antiarrhythmic drugs is a new and very interesting field of challenges to prevent atrial fibrillation onset and control recurrences.
The study aimed to know if there is some limit of age to make an effective treatment, and which systolic and diastolic values are necessary to achieve to stop atrial fibrillation.
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