Authors: Puguh Riyanto, Retno Indar Widayati, Diah Adriani Malik.
Background: Changes in skin integrity can cause extensive skin damage and become risk factor for infection. This is what makes preterm infants have a higher risk for infection because of the underdeveloped stratum corneum as a barrier. Erythema, scale, prick marks, excoriation, erosion, or crusting may represent barrier impairement. Those condition could be assessed through clinical observation using skin condition score. The application of natural emolient such as corn oil with its antimicrobial properties could be a potentially beneficial topical agent for preterm infants.
Aim: proving effectiveness of topical corn oil on reducing the risk of impaired skin integrity of preterm infants with parameters skin condition score.
Methods: Searching the electronic database Pubmed-MEDLINE, Scopus, ProQuest, Scopus, Cochrane library, ClinicalTrials.gov, and Google Scholar
Results: There are 5 articles included in the qualitative study and 2 articles included in the meta-analysis. The meta-analysis of the effect of topical corn oil compared with control showed the heterogenity test with Tau2=0.16 df=1; p=0.12, I2=58%. The value of the Q statistic was z value = 2,53 (p < 0.01). The results of the overall meta analysis show that the overall risk ratio value between intervention group compared to control was 0,41[-0.20, 0.82] (p<0.01). It means that the administration of topical corn oil can significantly reduce the risk of impaired skin integrity on preterm infants.
Conclusions: The application of corn oil can significantly reduce the risk of impaired skin integrity on preterm infants.
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