Authors: Shoshi Inooka.
DNA crown cells are artificial cells which possess outer membranes covered in DNA. Various types of DNA crown cells (artificial cells) are easily prepared by incubation in egg white. However, the practical applications of such DNA Crown Cells remain unclear
Previously, I synthesized DNA crown cells using DNA from the antibiotic-producing Streptomyces griseus and noted that the antibiotic was produced in a co-culture with yeast (beer) and egg white containing DNA crown cells.
However, many questions remain. In particular, it was unclear whether DNA crown cells themselves are associated with antibiotic production, as egg white was present with the DNA crown cells. Thus, to eliminate the effects of egg white, DNA crown cells were recovered from egg white and we then examined whether antibiotic production was observed in co-culture with DNA crown cells and Yeast.
I confirmed antibiotic production in Yeast and DNA crown cell co-culture. I also discussed the potential applications of co-cultures of DNA crown cells and yeast, as different types of DNA crown cell may yield useful results for other applied fields.
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